ea0003p235 | Reproduction | BES2002
Rae M
, Harlow C
, Davidson L
, Hillier S
Introduction Tissue remodelling, and deposition of extracellular matrix and basement membrane are critical processes in the formation and development of ovarian follicles. Collagen is a major component of the ECM. Though there is substantial literature concerning the breakdown of collagen in the ovary, little attention has been given to the processes of collagen formation and deposition. Lysyl oxidase (LO) is critical in this process, being the enzyme responsible for the final...